The Paramount Network series announced a number of new and returning cast members for the upcoming season.
The actor's romcom with Reese Witherspoon was released in 2002.
The 48-year-old actor tells ET that he's 'up for' reprising his role in the 2002 flick.
ET spoke with Lucas at the Hollywood Foreign Press Association's Annual Grants Banquet.
The medical miracle drama comes to theaters on April 17, 2019.