From On-Screen Co-Stars to Real-Life Romance

The Gotham co-stars took their romance to the real world in September 2015, announcing that they were expecting their first child together.

Jolie and Pitt caused a scandal when they "fell in love" on the set of Mr. & Mrs. Smith, despite the fact that Pitt was still married to Jennifer Aniston at the time. Despite their scandalous start, the couple has officially been together since 2006, were married August 2014, and are parents to six children.

Despite playing on-again/off-again couple Jackie and Kelso on That '70s Show, Kunis and Kutcher didn't begin dating in real life until April 2012. They welcomed daughter Wyatt in October 2014.

Affleck and Garner began dating after playing comic book couple Daredevil and Elektra in the 2003 Daredevil adaptation. They were married in 2004 and are parents to three children.

Stone was cast as Gwen Stacy opposite Andrew Garfield's Peter Parker in the franchise reboot The Amazing Spider-Man. Director Marc Webb noted the pair's chemistry during casting, which sparked an off-screen romance that began while the pair was shooting the first film in 2011.

The Disney Channel sweethearts met on the set of High School Musical in 2005 and dated until 2010.

Dewan and Tatum both began their entertainment careers as dancers, which led to a serendipitous turn as co-stars in the 2006 dance film Step Up. The couple began dating shortly after filming wrapped, were married in 2009, and welcomed daughter Everly in 2013.

The Big Bang Theory co-stars proved life imitates art as they secretly dated for about two years until 2009 -- at the same time their characters were romantically linked on the show.

The pair met while playing "freak" love interests Nick Andopolis and Lindsay Weir on the short-lived Judd Apatow show Freaks and Geeks (Segel personally composed a love song for his character to sing to Cardellini's), and dated for a few years following the show's cancellation.

Gellar and Prinze first met while filming the 1997 teen horror flick I Know What You Did Last Summer, but didn't begin dating until 2000. They went on to star opposite each other in the Scooby-Doo live-action films and welcomed daughter Charlotte in 2009 and son Rocky in 2012.

The True Blood co-stars, who began dating after filming the show's pilot in 2007, went from playing the undead to "'til death do us part" when they wed in 2010. Their family of six now includes fraternal twins, born in 2012, as well as Moyer's son and daughter from a previous relationship.

Goodwin met her real-life Prince Charming when she was cast opposite Josh Dallas in ABC's fairytale drama Once Upon a Time in 2011. The couple married in April 2014 and welcomed their first child in May 2014. 

Gilmore Girls star Alexis Bledel met her husband-to-be Vincent Kartheiser when she appeared in a recurring role on Mad Men in 2012. The couple were married in June 2014.

The Jumper co-stars met on the set of the 2008 science fiction film and welcomed their first child, daughter Briar Rose, in October 2014.