The 'Deadpool' star was honored with the Entertainer of the Year award at Sunday's show.
Ryan Reynolds continues to champion an important issue.
The Deadpool star was named "Entertainer of the Year" at this year's Critics’ Choice Awards, where he took a moment to highlight two organizations that help children with illness – many of whom find a somewhat unlikely hero in Reynolds’ “merc with a mouth” -- while also paying respect to two young fans who lost their lives.
"I would like to dedicate this honor to the Make-a-Wish foundation, and the Sick Kids Foundation of Toronto," the 40-year-old actor said in his speech. "Two incredible organizations who do so much for so many kids in need."
"And I would also like to dedicate this award to the memories of my friends Connor McGrath and Grace Bowen," he added. "They didn't lose the battle, they started a fight and it's up to us to finish it."
Later in the show, Reynolds won Best Actor in a Comedy for Deadpool, where, unprepared to say anything else, he gave a shoutout to Tom Hanks.
"You're a huge influence on me," Reynolds told the Sully star, who was in attendance. "My two-year-old daughter -- the first full sentence she ever said was, 'There's no crying in baseball.' I'm not kidding."
Not bad first words to have!
Watch the video below to see Reynolds rave to ET about baby No. 2 and wife Blake Lively.